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Children Who Are Considered Obese Are Twice As Likely To Develop Multiple Sclerosis, According To New Study

Children who are considered obese could face more than double the risk of developing multiple sclerosis (MS) as adults, according to a new study from the Karolinska Institute in Stockholm. 

MS can impact the brain and spinal cord. It causes a range of potential symptoms such as problems with arm or leg movement, sensation, balance, or vision. MS can also lead to serious disability throughout one’s life. 

The Karolinska Institute will be presenting the findings of their study at the European Congress on Obesity in May in Venice. 

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Previous research has speculated that there is a link between high body mass index (BMI) in adolescence and a larger risk of MS in adulthood, however, most of the studies that suggested this were using self-reported data, so it was difficult to arrive at an accurate conclusion. 

With this particular study, the researchers wanted to evaluate the risk of developing MS by utilizing a large population of obese children to compare with the general population.

According to reports from the Guardian, researchers analyzed data from the Swedish Childhood Obesity Treatment Register, which utilizes a database known as Boris. This institute is one of the world’s largest registries for treatment of childhood obesity.

The study looked at data from more than 21,600 children with obesity aged two to 19 who joined the registry between 1995 and 2020. The children, on average, started their treatment for obesity when they were around 11-years-old. They also compared that data to more than 100,000 children without obesity to get the greatest comparison possible. 

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The children monitored in the study were tracked for about six years, and during the follow-up period, 28 of those with obesity were diagnosed with MS (0.13% of the group) and 58 in the group without obesity (0.06% of the group). 

Within both groups, the average age of the MS diagnosis was 23-years-old. 

“Despite the limited follow-up time, our findings highlight that obesity in childhood increases the susceptibility of early-onset MS more than twofold,” the authors stated. 

“One of the effects of obesity in childhood is that it causes a low-grade but chronic inflammation, and most probably this inflammation increases the risk to develop several diseases such as MS,” study authors, Emilia Hagman, an associate professor, and Prof Claude Marcus, said.

“It is also believed that chronic low-grade inflammation increases the risk for other such diseases as asthma, arthritis, type 1 diabetes, and some forms of cancers. However, we know that weight loss reduces the inflammation and most likely the risk to develop such diseases.”

Scientists In The UK Working On A Bra That Can Detect And Monitor Breast Cancer 

Scientists in the UK are currently developing a device that would fit inside of a bra to monitor whether or not a breast cancer tumor is growing. 

The researchers behind the device are hoping that the device will ideally provide a new non-invasive method of detecting tumor growth so patients can get the information in their own home. 

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The device itself is being developed by Nottingham Trent University’s medical technologies innovation facility. According to the Guardian, the device will use an electrical current to “scan and detect tiny changes in fluids inside and outside cells in the breast.”

Tumor tissues are more dense than healthy tissue, and they contain less water. This is why the device will be able to measure changes in the growth of the tumor in real time, and can detect tumors as little as 2 millimeters. 

The researchers are also stating that the device could be inserted into a patient’s bra that they already own. Additionally, they’re developing a new bra that would have the device already incorporated into it. The device will be able to record and send data to the individual wearing it and their medical team via smartphone. 

Researchers are hoping to get the device in a clinical trial within the next few years. 

“The technology would measure changes in breast tissue and help improve a patient’s chance of survival. Breast cancer can grow so quickly; it could be 1mm in six months or 2mm in six weeks. This would be an additional measure to see how fast the tumor grows.” said Dr Yang Wei, an expert in electronic engineering at NTU. 

“We are opening the door to the investigation of an alternative breast cancer detection that could be done in the comfort of a patient’s home, conserving essential hospital resources whilst still providing a viable solution to detect early signs of cancer.”

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Cancer Research UK released data that showed there are more than 55,000 new cases of breast cancer in the UK alone every year, and more than 11,000 deaths. Of all those new cases, about 23% are completely preventable. 

The research team is hoping that the device will improve the vitals work of monitoring tumors. MRI scans in breast cancer patients can sometimes occur months apart from each other, which could lead to significant growth in the tumor itself. The device will ideally simplify this process and give the patient the opportunity to monitor their cancer themselves. 

Dr Simon Vincent, the director of research, said this “research on improved detection and treatment of breast cancer is urgently needed.”

“While this new technology could offer a new way to monitor the growth of breast cancer tumors and we look forward to seeing the final results, the device has not yet been tested on people and there’s a lot more we need to understand before we can consider whether or not it could be used in medical settings,” he said.

“Anyone affected by breast cancer can speak to Breast Cancer Now’s expert nurses by calling our free helpline on 0808 800 6000 for information and support.”

whale

Gray Whale Sighted Near New England 200 Years After Species Were Thought To Be Extinct In The Atlantic Ocean 

A gray whale has been confirmed by scientists to be seen near New England, two centuries after it was thought that the whale was extinct in the Atlantic Ocean. While this is an exciting discovery for science, experts are saying that it also illustrated the impact of climate change on sea life and their migration patterns. 

The gray whale was initially seen by members of the New England Aquarium in Boston while they were flying 30 miles south of Nantucket, Massachusetts. They sighted the whale, which can weigh up to 60,000 pounds, on March 1st, according to the Guardian

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The gray whale typically lives in the northern Pacific Ocean, and seemingly vanished from the Atlantic ocean around the 18th century. Within the last 15 years, there have been about five potential observations of the whole in the Atlantic and Mediterranean waters. 

The aquarium stated that the whale found this month was likely the same what that was spotted late last year in Florida. 

The aquarium researchers who recently found the whale near Massachusetts were skeptical after their initial observations, however, after circling the area for about 45 minutes, they were able to take more detailed pictures and confirm it was a gray whale. 

Orla O’Brien, an associate research scientist with the Anderson Cabot Center for Ocean Life at the New England Aquarium, said that at first she “didn’t want to say out loud what it was, because it seemed crazy,” but was luckily proven to be right with ehr initial observations. 

While scientists are excited to see the gray whale in the Atlantic, they stated its presence likely has to do with the warming of the planet brought on by climate change. 

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The North-west Passage connects the Atlantic and Pacific Oceans through the Arctic Ocean in Canada. In recent years, during the summer the passage has lacked a presence of ice, which prevents animals like the gray whale from passing through. 

Now, scientists are predicting that gray whales are able to travel through the passage during the summer months, when they otherwise would typically be blocked from ice. 

According to O’Brien, the gray whale’s recent sighting near New England is “a reminder of how quickly marine species respond to climate change, given the chance.”

When commercial whaling was more common, gray whales were almost hunted to extinction. Luckily today, the gray whale population has recovered immensely, so much so that they’re considered to be a species of “least concern” by the International Union for Conservation of Nature.” 

The organization also stated that the western population of gray whales that lives off Asia is still considered to be endangered. 

When compared to other, more commonly sighted, whales off the coast of New England, such as humpback whales, gray whales can be identified by their lack of dorsal fin and marks of spots or smears of color. Gray whales also make more gurgling, grunting, croaking noises, while humpback whales are known for their more haunting high pitched songs. 

saturn

Astronomers Uncover Secret Ocean On One Of Saturn’s Smallest Moons 

Astronomers have uncovered increasing evidence that one of Saturn’s smallest moons, named Mimas, has a global ocean beneath its icy surface. This is a significant revelation in the overall search for water on other planets, as water is an essential building block for all life, further fueling the potential for discovering habitable worlds in deep space. 

Scientists used to think Mimas was just a big ice chunk before NASA went on their Cassini mission orbiting Saturn, and its 146 moons, from 2004 to 2017. 

Mimas was first discovered in 1789 by English astronomer William Herschel, and was first photographed in 1980 using the Voyager probes. Mimas is covered in craters, with the largest one being 80 miles across. 

Through the Cassini mission, astronomers found that the moon takes around 22 hours to orbit Saturn, and is about 115,000 miles from Saturn. Data also showed that Mimas’ rotation and orbital motion is triggered by the moon’s interior. 

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According to reports, in 2014 European researchers determined that the core of Mimas is either rigid, elongated, rocky, or has a subsurface ocean causing its rotation and motion. Observatoire de Paris astronomer Dr. Valéry Lainey and his colleagues analyzed the orbital motion data to get a clearer conclusion, and their findings were published Wednesday in the journal Nature

Through this study, the team was able to determine that the moon’s spin and orbital motion didn’t match up with the theory that Mimas had a rocky core, and instead, the evolution of its orbit suggests an internal ocean that shaped its motion, Lainey explained. 

“This discovery adds Mimas to an exclusive club of moons with internal oceans, including Enceladus and Europa, but with a unique difference: its ocean is remarkably young, estimated to be only 5 (million) to 15 million years old,” said study co author Dr. Nick Cooper.

The team was able to determine the origin and age of Mimas’ ocean by analyzing how the moon responded to Saturn’s gravitational forces. 

“Internal heating must come from the tides raised by Saturn on Mimas. These tidal effects have induced friction inside the satellite, providing heat,” Lainey said. 

The study stated that they suspect the ocean is around 12 to 19 miles below the moon’s ice exterior. Astronomically speaking the ocean is very young, which means there wouldn’t be any outward signs of activity on the surface.

This discovery is a huge moment for science in general, as it could shift the ways in which astronomers think about moons in our solar system. 

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“If Mimas hides a global ocean, this means that liquid water could lie almost anywhere. We already have serious candidates for global oceans (on moons such as) Callisto, Dione and Triton,” Lainey said. 

“The existence of a recently formed liquid water ocean makes Mimas a prime candidate for study, for researchers investigating the origin of life,” Cooper said.

“It may be time to observe other seemingly quiet moons across the solar system that could be hiding conditions that can support life,” the study authors said.

“Lainey and colleagues’ findings will motivate a thorough examination of mid-sized icy moons throughout the Solar System,” wrote Drs. Matija Ćuk and Alyssa Rose Rhoden in an article that accompanied the study.

Rhoden has also written research about a “stealth” ocean on Mimas.

“Basically, the difference between our 2022 paper and this new paper is that we found an ocean could not be ruled out by Mimas’ geology, whereas they are actually detecting the signature of the ocean within Mimas’ orbit. It is the strongest evidence we have, so far, that Mimas really does have an ocean today,” Rhoden said.

“Mimas certainly demonstrates that moons with old surfaces can be hiding young oceans, which is pretty exciting. I do think we can speculate as to moons having developed oceans much more recently than we often assume,” Rhoden said.

hubble

Astronomers Detect Water Vapor On Small Exoplanet In “Landmark Discovery”

Astronomers have utilized the Hubble Space Telescope to make a “landmark discovery” of water molecules on a small exoplanet located 97 light-years away from Earth, according to reports from CNN

The planet is scientifically named GJ 9827d, and is about twice Earth’s diameter, and according to a new report published last week in The Astrophysical Journal Letters, is the smallest exoplanet that has been found to have water vapor in its atmosphere. 

While the presence of water on any planet could be a sign of life, the astronomers involved in this research said it was unlikely that this planet has life on it due to its hot temperature that likely turns the water in the atmosphere to steam. 

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“Water on a planet this small is a landmark discovery. It pushes closer than ever to characterizing truly Earth-like worlds,”  said study coauthor Laura Kreidberg, managing director of the atmospheric physics of exoplanets department at the Max Planck Institute for Astronomy in Heidelberg, Germany, in a statement.

The planet itself is reported to reach temperatures of 800 degrees Fahrenheit (427 degrees Celsius), hence the conclusion that it’s inhospitable. 

“This would be the first time that we can directly show through an atmospheric detection, that these planets with water-rich atmospheres can actually exist around other stars. This is an important step toward determining the prevalence and diversity of atmospheres on rocky planets,” said study coauthor Björn Benneke, professor at the University of Montreal’s Trottier Institute for Research on Exoplanets, in a statement

“Our observing program, led by principal investigator Ian Crossfield of (the University of Kansas) in Lawrence, Kansas, was designed specifically with the goal to not only detect the molecules in the planet’s atmosphere, but to actually look specifically for water vapor. Either result would be exciting, whether water vapor is dominant or just a tiny species in a hydrogen-dominant atmosphere,” said lead study author Pierre-Alexis Roy, a doctoral student at the University of Montreal’s Trottier Institute, in a statement

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According to the study, astronomers have observed GJ 9827d during 11 transits within the past three years. 

“Until now, we had not been able to directly detect the atmosphere of such a small planet. And we’re slowly getting into this regime now. At some point, as we study smaller planets, there must be a transition where there’s no more hydrogen on these small worlds, and they have atmospheres more like Venus (which is dominated by carbon dioxide),” Benneke said. 

“Observing water is a gateway to finding other things. This Hubble discovery opens the door to future study of these types of planets by the James Webb Space Telescope. JWST can see much more with additional infrared observations, including carbon-bearing molecules like carbon monoxide, carbon dioxide, and methane. Once we get a total inventory of a planet’s elements, we can compare those to the star it orbits and understand how it was formed,” said study coauthor Thomas Greene, astrophysicist at NASA’s Ames Research Center in California’s Silicon Valley. 

“We can hardly wait to see what those data reveal. Hopefully, we can now settle the question of water worlds once and for all,” Kreidberg stated.

Formally Unknown Relative Of The T. Rex Discovered In New Mexico

A formally unknown relative of the Tyrannosaurus rex has been discovered in New Mexico, according to a new study released in the Journal Scientific Reports.

scientist

Animal Testing Could Come To An End With 3D-Printed Chip That Shows Body’s Reaction To Drugs 

Researchers at the University of Edinburgh have designed a new “body-on-chip” that perfectly mimics how medicine travels through the body, which could eliminate the need for animal testing when it comes to drug and medication development. 

Typically thousands of animals are used every year around the world during the early stages of developing medicines, however, many of these drugs don’t end up showing any clinical benefit. 

According to reports from The Guardian, the device is the first of its kind, and was made using a 3D printer. The chip itself has five compartments that replicate the human heart, liver, lungs, kidney, and brain. Each compartment is connected by little channels that are meant to replicate the human circulatory system. 

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Liam Carr is the inventor of this device, and he explained that the plastic chip uses positron emission tomography (PET) scanning to produce 3D images showing what is going on inside the replicated “organs.”

“The PET imagery is what allows us to ensure the flow of new drugs being tested is even,” Carr explained

“This device is the first to be designed specifically for measuring drug distribution, with an even flow paired with organ compartments that are large enough to sample drug uptake for mathematical modeling. Essentially, allowing us to see where a new drug goes in the body and how long it stays there, without having to use a human or animal to test it.”

“The platform is completely flexible and can be a valuable tool to investigate various human diseases, such as cancer, cardiovascular diseases, neurodegenerative diseases and immune diseases. Because of this flexibility, the uses are bound only by the availability of these cell models, and the scientific questions we can think of,” Carr stated.

“For example, we could have a fatty liver disease model in the device and use this to see how having a diseased liver affects other organs such as the heart, brain, kidneys, etc, and could even combine multiple diseased cell models to see how diseases can interfere with each other.”

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Dr. Adriana Tavares of Edinburgh’s Center for Cardiovascular Science is Carr’s supervisor, and she explained that by linking the five organs together in this device, scientists can effectively study how new drugs may impact a patient’s entire body. 

“This is a really important area of medical research, as we continuously learn about how diseases traditionally perceived to be restricted to an organ or system can have diverse effects across other distant organs or different interconnected systems.”

“Devices such as the body-on-chip platform are essential to unravel the mechanisms underlying systemic effects of local diseases as well as investigate off-target effects of drugs, which might be therapeutically useful or detrimental,” she added

“This device shows really strong potential to reduce the large number of animals that are used worldwide for testing drugs and other compounds, particularly in the early stages, where only 2% of compounds progress through the discovery pipeline.”

“This non-animal approach could significantly reduce cost of drug discovery, accelerate translation of drugs into the clinic, and improve our understanding of systemic effects of human diseases, by using models that are more representative to human biology than animal models,” she concluded. 

ice

Study Finds Earth’s Carbon Dioxide Levels Are Highest In Human History 

A new study has found that the current carbon dioxide levels on Earth are the highest they’ve been in all of human history.

sphinx

Scientists Reveal Evidence That Supports A Possible Origin Story For The Great Sphinx

Space scientist and geologist Farouk El-Baz initially theorized that wind played a major role in shaping the famous Great Sphinx of Giza 40 years ago. Now, a new study has revealed evidence that suggests El-Baz’s theory might be correct. The theory states that wind played a major role in shaping the initial structure of the Great Sphinx before ancient Egyptians added the surface details. 

The theory is being supported based on a team of scientists in New York University’s Applied Mathematics Laboratory who worked to replicate the conditions the ancient Egyptians faced 4,500 years ago; which is when scientists believe the statue was likely built.

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“Our findings offer a possible ‘origin story’ for how Sphinx-like formations can come about from erosion. Our laboratory experiments showed that surprisingly Sphinx-like shapes can, in fact, come from materials being eroded by fast flows,” said senior study author Leif Ristroph, an associate professor at New York University’s Courant Institute of Mathematical Sciences, in a news release

The team of researchers created clay-model landforms of compact sand which typically naturally occurs from the wind in exposed desert regions. They also washed the formations with a fast stream of water to represent the wind. 

According to CNN’s Taylor Nicioli, “based on the composition of the Great Sphinx, the team used harder, non-erodible inclusions within the featureless soft-clay mound, and with the flow from the water tunnel, the researchers found a lion form had begun to take shape.”

“Within the desert, there are yardangs that exist that naturally look like seated or lying animals with raised heads. Some of them look so much like a seated lion, or a seated cat, that they’re sometimes called Mud Lions. … Our experiments could add to the understanding of how these yardangs form,” Ristroph told CNN.

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It is believed that the Great Sphinx of Giza was carved from a single piece of limestone. The theory emphasizing the wind’s role in creating the 66-foot formation was initially featured in a 1981 Smithsonian Magazine article by El-Baz. 

“The premise was based on leading work by the late planetary geologist Ronald Greeley, who had simulated wind tunnels to explore how wind erosion can shape structures in the desert,” El-Baz told CNN

Salima Ikram, distinguished university professor of Egyptology at the American University in Cairo, questioned the theory: “Once the Great Sphinx was carved, nature played a part in its further formation, but it is unlikely that the original form was based on a yardang (which are generally of mud — this is limestone) as there are significant quarry marks and working marks surrounding it.” 

“There is too much evidence of human intervention in the construction of the Great Sphinx to make the yardang theory feasible,” Ikram said.

The New York University researchers said their results “suggest that Sphinx-like structures can form under fairly commonplace conditions, but the findings don’t resolve the mysteries behind yardangs and the Great Sphinx.

“t’s not so black and white. … No one says this is an entirely human carved thing and no one says it’s entirely nature carved. The question is how much was naturally existing and then further modified. What our (study) would do is tell you that much of the head base, the neck and the paws, much of that is possible to carve by nature, by erosion,” Ristroph told CNN.

saturn

Saturn’s Rings Will ‘Disappear’ From Earth’s View In 2025

Saturn is one of the most well-known planets in our solar system based on their wondrous rings. People can often view the planet using simple telescopes throughout the year when it’s visible, however, scientists are now saying in 2025, the famous rings around Saturn will no longer be visible from our views on Earth. 

Saturn’s rings are thought to be made up of pieces of comets, asteroids, chunks of ice and shattered moons that drifted towards the planet and were shredded by its powerful gravitational force. 

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According to a study published by Metro, scientists don’t know exactly how old the rings are, however, it is estimated that they formed 400 million years ago, which is very young in terms of cosmic bodies. 

Metro also has reported that scientists know the rings are disappearing, with pieces falling off as icy rain in Saturn’s atmosphere. 

Scientists predict that it will take at least 100 million years for the rings to completely disappear, however, for us on Earth, an optical illusion will make it seem as though they already disappeared in the coming years. 

According to Katherine Fidler of Metro: “The rings may be massive in one dimension, but in another, they’re miniscule – measuring just ten meters thick. 

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This isn’t a problem right now, because Saturn isn’t in perfect alignment with Earth – it’s tilted at about a 9 degree angle. Next year, that will have decreased to about 3.7 degrees.”

Starting in 2025, the way Saturn will be tilted will be directly horizontal from Earth’s view, meaning its rings will look too thin to actually see. 

Fidler described the view as like trying to look at a piece of paper turned to its side from across a football field. 

Since the planet is constantly inclining, however, the optical illusion won’t last that long, as Saturn will continue to move during its 29.5 year cycle.